K. Kostarelos

This paper demonstrates that graphene oxide nanosheets loaded with a TLR7/8 agonist can reprogram tumor-associated macrophages in GBM to a pro-inflammatory state, reducing tumor burden.

This study designs graphene oxide-based nanosheets to form stable complexes with the TLR7/8 agonist R848, preserving its biological activity and demonstrating effective macrophage activation.

This study uses human lung organoids to model pulmonary responses to carbon nanomaterials, showing MWCNTs cause pro-fibrotic effects while GO does not.

This paper introduces a graphene-based thin film microelectrode technology for high-resolution in vivo neural recording and stimulation, showing low impedance, high charge injection, and good biocompatibility.

This study investigates how the lateral size of graphene oxide affects its uptake mechanisms and intracellular fate in mammalian cells over time.

This study induces transient reprogramming of neonatal rat cardiomyocytes with OSKM factors, leading to dedifferentiation and increased proliferation but not full pluripotency.

This study evaluates graphene oxide as a 2D platform for siRNA delivery without surface modification, showing efficient internalization but limited gene silencing due to rapid siRNA release.

This paper uses lipid-based nanoparticles to capture and analyze tumor-specific proteins in blood, identifying potential cancer biomarkers through mass spectrometry.