Author

D. Dicker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

A. Lev· 2 shared S. Zhang· 2 shared W. El-Deiry· 2 shared A. Lulla· 1 shared L. Zhou· 1 shared N. Ahsan· 1 shared P. Abbosh· 1 shared S. Zhao· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersCancer Biology

A. Lev

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2 papers

Recent·Most cited

HIF1α inhibition by dual targeting of CDK4/6 and HSP90 reduces cancer cell viability including Rb-deficient cells

S. Zhao, L. Zhou, D. Dicker, A. Lev, S. Zhang, W. El-Deiry

This study shows that combining CDK4/6 and HSP90 inhibitors reduces HIF1 expression and cancer cell viability, including in Rb-deficient cells.

bioRxiv · Oct 20, 2020 · PreprintCancer Biology

P53-independent restoration of p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9

X. Tian, N. Ahsan, A. Lulla, A. Lev, P. Abbosh, D. Dicker, S. Zhang, W. El-Deiry

PG3-Oc restores p53 pathway signaling in mutant-p53 tumors through ATF4 modulation by ERK1/2 and CDK9, inducing p53 effector genes for cell death and tumor suppression.

bioRxiv · Oct 20, 2020Cancer Biology