Author

W. El-Deiry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Zhang· 3 shared A. Lev· 2 shared D. Dicker· 2 shared L. Carlsen· 2 shared L. Zhou· 2 shared A. A. Seyhan· 1 shared A. Lulla· 1 shared A. Navaraj· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

S. Zhang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

miR-6883 downregulates HIF1α in colorectal and breast cancer cells

N. Jensen-Velez, L. Carlsen, W. El-Deiry

The paper shows miR-6883 reduces CDK4/6 and HIF1 in colorectal and breast cancer cells under normoxia and hypoxia, suggesting it as a potential therapeutic target for hypoxic cancers.

bioRxiv · Sep 5, 2023 · PreprintCancer Biology

HIF1α inhibition by dual targeting of CDK4/6 and HSP90 reduces cancer cell viability including Rb-deficient cells

S. Zhao, L. Zhou, D. Dicker, A. Lev, S. Zhang, W. El-Deiry

This study shows that combining CDK4/6 and HSP90 inhibitors reduces HIF1 expression and cancer cell viability, including in Rb-deficient cells.

bioRxiv · Oct 20, 2020 · PreprintCancer Biology

P53-independent restoration of p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9

X. Tian, N. Ahsan, A. Lulla, A. Lev, P. Abbosh, D. Dicker, S. Zhang, W. El-Deiry

PG3-Oc restores p53 pathway signaling in mutant-p53 tumors through ATF4 modulation by ERK1/2 and CDK9, inducing p53 effector genes for cell death and tumor suppression.

bioRxiv · Oct 20, 2020Cancer Biology

Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells

L. Zhou, K. Huntington, S. Zhang, L. Carlsen, E.-Y. So, C. Parker, I. Sahin, H. Safran, S. Kamle, C.-M. Lee, C.-G. Lee, J. A. Elias, K. S. Campbell, M. T. Naik, W. J. Atwood, , W. El-Deiry

This study shows MEK inhibitors reduce ACE2 and inflammatory cytokines, enhance NK cell activity, and block SARS-CoV-2 pseudovirus infection in human cells.

bioRxiv · Aug 2, 2020 · PreprintCell Biology