Author

D. Dobrev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Zoology· 1

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

E. Grandi· 3 shared H. Ni· 3 shared S. Morotti· 3 shared X. Zhang· 3 shared A. Bounas· 1 shared A. Endris· 1 shared A. Ngari· 1 shared A. R. Moussa Zabeirou· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersPhysiology

E. Grandi

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Author profile →

4 papers

Recent·Most cited

Enhanced Ca2+-Driven Arrhythmias in Female Patients with Atrial Fibrillation: Insights from Computational Modeling

X. Zhang, Y. Wu, C. Smith, W. E. Louch, S. Morotti, D. Dobrev, E. Grandi, H. Ni

This study uses computational models to show female atrial cardiomyocytes in AF have higher Ca2+-driven arrhythmia risk than males, with specific interventions identified to address these differences.

bioRxiv · Mar 4, 2024 · PreprintPhysiology

Dual effects of the small-conductance Ca2+-activated K+ current on human atrial electrophysiology and Ca2+-driven arrhythmogenesis: an in silico study

N. T. Herrera, X. Zhang, H. Ni, M. M. Maleckar, J. Heijman, D. Dobrev, E. Grandi, S. Morotti

This study uses in silico models to show that modulating the SK current in human atrial myocytes can both promote and prevent arrhythmias depending on the underlying mechanism.

bioRxiv · Jun 16, 2023Physiology

Integrative human atrial modeling unravels interactive PKA and CaMKII signaling as key determinant of atrial arrhythmogenesis

H. Ni, S. Morotti, X. Zhang, D. Dobrev, E. Grandi

This paper develops a computational framework to simulate human atrial electrophysiology and Ca2+-handling, revealing synergistic PKA and CaMKII signaling as key drivers of atrial arrhythmogenesis.

bioRxiv · Apr 27, 2022Physiology

Major threats to a migratory raptor vary geographically along the eastern Mediterranean flyway

S. Oppel, V. Arkumarev, S. Bakari, V. Dobrev, V. Saravia, S. Adefolu, L. Aktay Sozuer, P. T. Apeverga, S. Arslan, Y. Barshep, T. Bino, A. Bounas, T. Cetin, M. Dayyoub, D. Dobrev, , Tesf

The paper assesses geographic variation in threats to Egyptian Vultures along the eastern Mediterranean flyway using tracking, surveys, and interviews, finding differing mortality causes across regions.

bioRxiv · Dec 16, 2020Zoology