Cell BiologybioRxiv
An unbiased screen identified the Hsp70-BAG3 complex as a regulator of myosin binding protein C3 stability.
A. D. Thompson, M. J. Wagner, J. Rodriguez…·S. M. Day
A high-throughput compound screen identified JG98 and parthenolide as reducing MyBP-C levels, revealing the Hsp70-BAG3 complex as a regulator of MyBP-C stability in HCM.
DOI 10.1016/j.jacbts.2023.04.009