Author

D. G. Stupack

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. Barrie· 1 shared A. M. Mark· 1 shared A. Molinolo· 1 shared B. Gyorffy· 1 shared C. J. Diaz Osterman· 1 shared C. Jean· 1 shared D. C. Connolly· 1 shared D. D. Schlaepfer· 1 shared

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2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. M. Barrie

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1 paper

Recent·Most cited

Cancer BiologyeLifePeer-reviewedSep 3, 2019

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

C. J. Diaz Osterman, D. Ozmadenci, E. G. Kleinschmidt…·D. D. Schlaepfer

This study identifies FAK activity as a driver of platinum resistance in ovarian cancer by sustaining CSC survival and DNA repair, showing that FAK inhibitors combined with platinum can overcome resistance.

DOI 10.7554/elife.47327

mousebulk RNA-seq

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