ImmunologybioRxivPreprint
STING activation depends on ACBD3 and other phosphatidylinositol 4-phosphate-regulating proteins
R. D. Luteijn, S. R. van Terwisga, J. E. Ver Eecke…·F. J. van Kuppeveld
This study identifies ACBD3 and PI4P-regulating proteins as essential for STING activation and shows that modulating PI4P levels can enhance STING signaling and cytokine production.
DOI 10.1101/2022.10.17.512580