Author

D. Hishikawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. Shindou· 4 shared T. Shimizu· 4 shared F. Hamano· 3 shared K. Nagata· 2 shared A. Kanatani· 1 shared A. Okinaga· 1 shared F. Arai· 1 shared H. Kobayashi· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersBiochemistry

H. Shindou

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4 papers

Recent·Most cited

Impact of perinatal maternal docosahexaenoic acid-containing phospholipid synthesis on offspring growth and neurological symptoms

A. Kanatani, D. Hishikawa, K. Nagata, F. Hamano, K. Nakano, T. Okamura, T. Shimizu, H. Shindou, T. Nagamatsu, K. Yanagida

This study shows that maternal DHA-PL synthesis during fetal development affects offspring neuropsychiatric outcomes, but not postnatal growth or brain size.

bioRxiv · Jan 6, 2024 · PreprintBiochemistry

Lysophosphatidylcholine acyltransferase 1 controls the mitochondrial reactive oxygen species generation and survival of the retinal photoreceptor cells

K. Nagata, D. Hishikawa, H. Sagara, M. Saito, S. Watanabe, T. Shimizu, H. Shindou

This study shows that Lpcat1 deletion causes photoreceptor-specific apoptosis and increased mitochondrial ROS in mice, highlighting its role in lipid metabolism and retinal health.

bioRxiv · Oct 6, 2021Biochemistry

Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA.

F. Hamano, K. Matoba, T. Hashidate, T. Suzuki, K. Miura, D. Hishikawa, T. Harayama, K. Yuki, Y. Kita, N. N. Noda, T. Shimizu, H. Shindou

The paper identifies key residues and an acyl-CoA-binding pocket in mouse LPCAT2 using homology modeling, providing structural insights for drug development against PAF-related diseases.

bioRxiv · Oct 31, 2020Biochemistry

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

H. Kobayashi, T. Morikawa, A. Okinaga, F. Hamano, T. Hashidate-Yoshida, S. Watanuki, D. Hishikawa, H. Shindou, F. Arai, Y. Kabe, M. Suematsu, T. Shimizu, K. Takubo

This study maintains engraftable quiescent HSCs in culture for 1 month using low cytokines, hypoxia, and high fatty acids.

bioRxiv · Dec 6, 2018Cell Biology