Author

H. Sagara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

T. Shimizu· 2 shared C. Kato· 1 shared D. Hishikawa· 1 shared E. Fujita· 1 shared H. Shindou· 1 shared K. Furusho· 1 shared K. MIYAKE· 1 shared K. Nagata· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

T. Shimizu

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2 papers

Recent·Most cited

Lysophosphatidylcholine acyltransferase 1 controls the mitochondrial reactive oxygen species generation and survival of the retinal photoreceptor cells

K. Nagata, D. Hishikawa, H. Sagara, M. Saito, S. Watanabe, T. Shimizu, H. Shindou

This study shows that Lpcat1 deletion causes photoreceptor-specific apoptosis and increased mitochondrial ROS in mice, highlighting its role in lipid metabolism and retinal health.

bioRxiv · Oct 6, 2021Biochemistry

Nucleosides drive histiocytosis in SLC29A3 disorders by activating TLR7

T. Shibata, M. Taoka, S.-I. Saitoh, Y. Yamauchi, Y. Motoi, M. Komine, E. Fujita, R. Sato, H. Sagara, T. Ichinohe, M. Kawazoe, C. Kato, K. Furusho, Y. Murakami, R. Fukui, , K. MIYAKE

This study shows that TLR7 activation by accumulated nucleosides in lysosomes drives histiocytosis in SLC29A3 disorders.

bioRxiv · Dec 16, 2019 · PreprintImmunology