Cell BiologybioRxivPreprint
AraC binds the p75NTR transmembrane domain to induce neurodegeneration in mature neurons.
V. S. Lopes Rodrigues, P. Boxy, E. Sim…·L. Kisiswa
This study shows AraC binds p75NTR's transmembrane domain, causing neurodegeneration in mature neurons by disrupting NFκB signaling and activating JNK-mediated cell death.
DOI 10.1101/2021.12.01.470721