PhysiologybioRxiv
Deficiency of peroxisomal L-bifunctional protein (EHHADH) causes male-specific kidney hypertrophy and proximal tubular injury in mice
P. Ranea-Robles, K. Portman, A. Bender…·S. M. Houten
This study shows that EHHADH deficiency in mice causes male-specific kidney hypertrophy and proximal tubular injury, linked to androgen effects on peroxisomal metabolism.
DOI 10.34067/kid.0003772021