EMC is required for biogenesis and membrane insertion of Xport-A, an essential chaperone of rhodopsin-1 and the TRP channel
C. J. Gaspar, L. C. Vieira, J. C. Christianson, D. Jakubec, K. Strisovsky, C. Adrain, P. Domingos
The paper identifies Xport-A as an essential chaperone for rhodopsin-1 and TRP channel biogenesis, showing EMC-dependent membrane insertion is required for its function.
bioRxiv · Feb 1, 2021Cell Biology