Author

C. J. Gaspar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:Drosophila· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:genetic perturbation / CRISPR· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Adrain· 2 shared D. Jakubec· 1 shared J. C. Christianson· 1 shared J. C. Martins· 1 shared K. Strisovsky· 1 shared L. C. Vieira· 1 shared M. N. Melo· 1 shared P. Domingos· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

C. Adrain

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyiSciencePeer-reviewedDec 1, 2023

Xport-A functions as a chaperone by stabilizing the first 5 transmembrane domains of Rhodopsin-1

C. J. Gaspar, J. C. Martins, M. N. Melo…·P. M. Domingos

The paper proposes a model where Xport-A stabilizes the first 5 transmembrane domains of Rhodopsin-1 during its biosynthesis, acting as a chaperone but not affecting the full-length protein.

DOI 10.1016/j.isci.2023.108309

Drosophilaprotein structure

𝕏 PostBluesky

Cell BiologybioRxivFeb 1, 2021

EMC is required for biogenesis and membrane insertion of Xport-A, an essential chaperone of rhodopsin-1 and the TRP channel

C. J. Gaspar, L. C. Vieira, J. C. Christianson…·P. Domingos

The paper identifies Xport-A as an essential chaperone for rhodopsin-1 and TRP channel biogenesis, showing EMC-dependent membrane insertion is required for its function.

DOI 10.15252/embr.202153210

Drosophilaproteomics

𝕏 PostBluesky