Author

D. Konstantopoulos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

G. Kollias· 3 shared M. Sakkou· 3 shared A. Liakos· 2 shared C. Tzaferis· 2 shared M. Armaka· 2 shared M. Fousteri· 2 shared A. Kotanidou· 1 shared A. Prados· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

G. Kollias

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Urolithin A induces cardioprotection and enhanced mitochondrial quality during natural aging and heart failure

S. Liu, J. Faitg, C. Tissot, D. Konstantopoulos, R. Laws, G. Bourdier, P. A. Andreux, T. Davey, A. Singh, C. Rinsch, D. J. Marcinek, D. D'Amico

This study shows that Urolithin A improves mitochondrial function and cardiac health in aging and heart failure models.

bioRxiv · Aug 22, 2023 · PreprintCell Biology

Upregulation of CD55 complement regulator in distinct PBMC subpopulations of COVID-19 patients is associated with suppression of interferon responses.

M. G. Detsika, M. Sakkou, V. Triantafyllidou, D. Konstantopoulos, E. Grigoriou, K. Psarra, E. Jahaj, I. Dimpoulou, S. E. Orfanos, A. Tsirogianni, G. Kollias, A. Kotanidou

The paper identifies upregulated CD55 in PBMC subpopulations of severe COVID-19 patients, linked to reduced interferon responses.

bioRxiv · Oct 7, 2022 · PreprintImmunology

Single-cell chromatin and transcriptome dynamics of Synovial Fibroblasts transitioning from homeostasis to pathology in modelled TNF-driven arthritis

M. Armaka, D. Konstantopoulos, C. Tzaferis, M. D. Lavigne, M. Sakkou, A. Liakos, P. P. Sfikakis, M. A. Dimopoulos, M. Fousteri, G. Kollias

This study profiles single-cell transcriptomes and chromatin accessibility of synovial fibroblasts in TNF-driven arthritis, identifying disease-specific subtypes and key regulatory factors.

Genome Medicine · Jul 26, 2022Peer-reviewedCell Biology

miR-221/222 drive synovial fibroblast expansion and pathogenesis of TNF-mediated arthritis

F. Roumelioti, C. Tzaferis, D. Konstantopoulos, D. Papadopoulou, A. Prados, M. Sakkou, A. Liakos, P. Chouvardas, T. Meletakos, Y. Pandis, N. Karagianni, M. Denis, M. Fousteri, M. Armaka, G. Kollias

This study shows miR-221/222 promotes synovial fibroblast expansion and worsens TNF-mediated arthritis by regulating cell cycle and ECM pathways.

bioRxiv · Jul 22, 2022 · PreprintCell Biology