Cell BiologyGenome MedicinePeer-reviewed
Single-cell chromatin and transcriptome dynamics of Synovial Fibroblasts transitioning from homeostasis to pathology in modelled TNF-driven arthritis
M. Armaka, D. Konstantopoulos, C. Tzaferis…·G. Kollias
This study profiles single-cell transcriptomes and chromatin accessibility of synovial fibroblasts in TNF-driven arthritis, identifying disease-specific subtypes and key regulatory factors.