Author

D. Krappmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Geerlof· 1 shared A. J. Ohnmacht· 1 shared A. N. Jones· 1 shared A. Strobel· 1 shared A. Zanzoni· 1 shared B. Dohai· 1 shared B. Weller· 1 shared C. Brun· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. Geerlof

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The pharmacogenomic assessment of molecular epithelial-mesenchymal transition signatures reveals drug susceptibilities in cancer cell lines

A. J. Ohnmacht, G. Avar, M. K. Schübel, T. J. O'Neill, D. Krappmann, M. P. Menden

The paper assesses molecular EMT signatures in cancer cell lines to identify drug susceptibilities, showing EMT can predict responses to HSP90 inhibitors and enhance drug sensitivity through TGF-β stimulation.

bioRxiv · Jan 16, 2024 · PreprintCancer Biology

A gut meta-interactome map reveals modulation of human immunity by microbiome effectors

V. Young, B. Dohai, T. C. Hitch, P. Hyden, B. Weller, N. S. Heusden, D. Saha, J. F. Macgregor, S. B. Maseko, C.-W. Lin, M. Boujeant, S. A. Choteau, F. Ober, P. Schwehn, S. Rothballer, , P. Falter-Braun

The paper identifies a gut microbiome meta-interactome map showing how bacterial effectors modulate human immunity and are enriched in Crohn's disease.

bioRxiv · Sep 25, 2023 · PreprintMicrobiology

Modulation of pre-mRNA structure by hnRNP proteins regulates alternative splicing of MALT1

A. N. Jones, C. Grass, I. Meininger, A. Geerlof, M. Klostermann, K. Zarnack, D. Krappmann, M. Sattler

The paper shows hnRNP proteins modulate MALT1 pre-mRNA structure to regulate alternative splicing of exon7 by competing for RNA stem-loop binding.

bioRxiv · Oct 12, 2021Biochemistry