Author

V. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Pathology· 2 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. E. Wobus· 2 shared A. C. S. Barbosa· 1 shared A. Kaur· 1 shared A. Kolawole· 1 shared A. O'Broin· 1 shared A. Seekatz· 1 shared A. Strobel· 1 shared A. V. Schmidt· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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2 shared papersMicrobiology

C. E. Wobus

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A gut meta-interactome map reveals modulation of human immunity by microbiome effectors

V. Young, B. Dohai, T. C. Hitch, P. Hyden, B. Weller, N. S. Heusden, D. Saha, J. F. Macgregor, S. B. Maseko, C.-W. Lin, M. Boujeant, S. A. Choteau, F. Ober, P. Schwehn, S. Rothballer, , P. Falter-Braun

The paper identifies a gut microbiome meta-interactome map showing how bacterial effectors modulate human immunity and are enriched in Crohn's disease.

bioRxiv · Sep 25, 2023 · PreprintMicrobiology

Dicarboxylic acid supplementation protects from acute kidney injury via stimulation of renal peroxisomal activity

A. C. S. Barbosa, K. E. Pfister, T. Chiba, J. Bons, J. Rose, J. B. Burton, C. D. King, A. O'Broin, V. Young, B. Zhang, B. Sivakama, A. V. Schmidt, R. Uhlean, B. Schilling, E. S. Goetzman, S. Sims-Lucas

This study shows that DC8 supplementation reduces AKI markers and promotes peroxisomal FAO over mitochondrial FAO in mice with kidney injury.

bioRxiv · May 31, 2023Pathology

SMRT-AgRenSeq-d in potato (Solanum tuberosum) identifies candidates for the nematode resistance Gpa5

Y. Wang, L. H. Brown, T. M. Adams, Y. W. Cheung, J. Li, V. Young, D. T. Todd, M. R. Armstrong, K. Neugebauer, A. Kaur, B. Harrower, S. Oome, X. Wang, M. Bayer, I. Hein

The paper introduces SMRT-AgRenSeq-d, a method for identifying NLR resistance genes in potato, and applies it to find nine strong candidates for the nematode resistance gene Gpa5.

bioRxiv · Dec 8, 2022Plant Biology

Human neutrophils direct epithelial cell extrusion to enhance intestinal epithelial host defense during Salmonella infection

A.-L. E. Lawrence, R. P. Berger, D. R. Hill, S. Huang, V. K. Yadagiri, B. Bons, C. Fields, G. J. Sule, J. S. Knight, C. E. Wobus, J. Spence, V. Young, M. X. O'Riordan, B. Abuaita

This study shows human neutrophils enhance intestinal epithelial cell extrusion to reduce Salmonella burden during infection, beyond direct antimicrobial activity.

bioRxiv · Mar 25, 2022Microbiology

Human norovirus infection of primary B cells triggers immune activation in vitro

C. Mirabelli, M. K. Jones, V. Young, A. Kolawole, I. Owusu, M. Shan, B. H. Abuaita, I. Grigorova, S. K. Lundy, C. A. Lyssiotis, V. K. Ward, S. M. Karst, C. E. Wobus

This study shows human norovirus infects primary B cells, induces functional changes, and the NS1 protein affects B cell proliferation and metabolism in vitro.

bioRxiv · May 14, 2021 · PreprintMicrobiology

A novel real-time PCR assay panel for detection of common respiratory pathogens in a convenient, strip-tube array format

M. R. Hasan, H. Al Mana, V. Young, P. Tang, E. Thomas, R. Tan, P. Tilley

The paper develops and validates a real-time PCR assay (Respanel) for detecting respiratory pathogens, showing higher sensitivity than Resplex and comparable performance to FTDRP21.

bioRxiv · Oct 29, 2018Pathology

Spatial and Temporal Analysis of the Stomach and Small Intestinal Microbiota in Fasted Healthy Humans

A. Seekatz, M. Schnizlein, M. Koenigsknecht, J. Baker, W. Hasler, B. Bleske, V. Young, D. Sun

This study analyzes the microbiota composition in the stomach and small intestine of fasted healthy humans over time, finding greater variability in the duodenum and correlations with pH changes.

bioRxiv · Oct 26, 2018Microbiology