D. Saha

Partial alopecia area retains bulge hair follicle progenitor cells in Indian androgenetic alopecia patients

The paper identifies that progenitor cells persist in partially bald areas of Indian AGA patients but are absent in completely bald areas, suggesting a timeframe for therapeutic intervention.

Evaluation of melanocyte stem cell population in vitiliginous skin pre- and post-narrow-band UVB phototherapy

This study evaluates melanocyte stem cell and immune cell changes in vitiligo patients before and after narrow-band UVB phototherapy, finding increased MelSC re-population and reduced CD3+ T-cells.

Angiopoietin-like protein 2 mediates vasculopathy driven fibrogenesis in a mouse model of systemic sclerosis

This study identifies Angptl2 as a driver of fibrotic vasculopathy in a mouse model of SSc and shows that inhibiting its effects can reduce fibrogenesis.

Employing a honeybee olfactory neural circuit as a novel gas sensor for the detection of human lung cancer biomarkers

This paper uses honeybee olfactory circuits to detect human lung cancer biomarkers in breath, achieving high classification accuracy for both individual markers and complex mixtures.

A gut meta-interactome map reveals modulation of human immunity by microbiome effectors

The paper identifies a gut microbiome meta-interactome map showing how bacterial effectors modulate human immunity and are enriched in Crohn's disease.

Testing Adaptive Therapy Protocols using Gemcitabine and Capecitabine on a Mouse Model of Endocrine-Resistant Breast Cancer

This study tests adaptive therapy protocols using gemcitabine and capecitabine on a mouse model of endocrine-resistant breast cancer, finding improved survival with adaptive strategies over high-dose combination therapy.

Bacopa monnieri phytochemicals regulate fibroblast cell migration via modulation of focal adhesions

This study shows Bacopa monnieri extract enhances fibroblast migration through focal adhesion modulation, improving wound healing.

Harnessing insect olfactory neural circuits for noninvasive detection of human cancer

This paper uses insect olfactory neural circuits to detect human oral cancers by analyzing VOCs from cell cultures, achieving fast and reliable classification.

Mindin is essential for cutaneous fibrogenesis in a new mouse model of systemic sclerosis

This study identifies Mindin as a key driver of fibrosis in a new mouse model of systemic sclerosis, showing its role in inducing inflammation and collagen production in fibroblasts.

Structural basis for targeting the human T-cell leukemia virus Tax oncoprotein and syntenin-1 interaction using a small molecule

This study identifies the structural basis of Tax-1 interaction with syntenin-1 and demonstrates small-molecule inhibition of this interaction to target HTLV-1.

Exostosin-1 Glycosyltransferase Regulates Endoplasmic Reticulum Architecture and Dynamics

This study shows that Exostosin-1 glycosyltransferase regulates ER morphology and dynamics, affecting cell size and metabolic processes in mammalian cells.

Docosahexaenoic acid (DHA), a nutritional supplement, modulates steroid insensitivity in asthma

This study shows DHA improves steroid sensitivity in asthma models and is lower in steroid-insensitive asthmatics.

The superoxide dismutase mimetic GC4419 enhances tumor killing when combined with stereotactic ablative radiation

GC4419 enhances tumor killing when combined with stereotactic ablative radiation in NSCLC and other cancers by generating hydrogen peroxide and altering inflammatory signaling.

Remote-controlled insect navigation using plasmonic nanotattoos

This paper develops a non-invasive method to remote control insects using plasmonic nanotattoos that preserve tissue integrity and enable environmental sensing.

Explosive sensing with insect-based biorobots

This study demonstrates a biorobotic chemical sensing system using locust brain signals to detect and distinguish explosive vapors rapidly.

The regulatory factor ELF1 triggers a critical wave of transcription in the antiviral response to type I interferon

This paper identifies ELF1 as a non-canonical regulator of antiviral ISG expression, showing it amplifies and prolongs the type I interferon response by inducing a distinct set of antiviral genes.