Evolutionary BiologyPLOS Computational BiologyPeer-reviewed
Two levels of selection of rhythmicity in gene expression: energy saving for rhythmic proteins and noise optimization for rhythmic transcripts
D. Laloum, M. Robinson-Rechavi
The paper investigates evolutionary origins of gene expression rhythms, finding that protein rhythmicity reduces energy cost while mRNA rhythmicity optimizes noise and allows adaptive flexibility.
DOI 10.1371/journal.pcbi.1010399