Chronic oxytocin-driven alternative splicing of CRFR2α induces anxiety
J. Winter, M. Meyer, I. Berger, S. Peters, M. Royer, M. Bianchi, S. Stang, D. Langgartner, S. O. Reber, K. Kuffner, A. K. Schmidtner, F. Hartmann, A. Bludau, O. J. Bosch, D. A. Slattery, , B. Jurek
This study shows chronic oxytocin increases soluble CRFR2, linked to anxiety, while acute oxytocin reduces anxiety via membrane-bound CRFR2.
bioRxiv · Aug 19, 2020Animal Behavior & Cognition