Author

D. Ly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

M. L. Sanderson-Smith· 2 shared A. C. Pollock· 1 shared A. J. Bergman· 1 shared A. J. Cork· 1 shared A. Tajii· 1 shared B. G. Wouters· 1 shared B. L. Schulz· 1 shared B. M. Moran· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

M. L. Sanderson-Smith

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Recent evolution of large offspring size and post-fertilization nutrient provisioning in swordtails

C. Y. Payne, D. Ly, R. A. Rodriguez-Soto, D. L. Powell, N. D. Robles, T. R. Gunn, J. J. Baczenas, A. J. Bergman, A. C. Pollock, B. M. Moran, J. C. Baker, D. Reznick, M. Schumer

This study compares reproductive strategies between two swordtail fish species, finding that X. malinche produces larger, more resilient offspring through extended post-fertilization nutrient provisioning.

Proceedings of the Royal Society B: Biological Sciences · Feb 11, 2026Peer-reviewedEvolutionary Biology

Uncovering structural features that control substrate specificity in a Lactobacillus chlorogenic acid esterase

K. K. Omori, T. L. S. Okumura, N. B. Carl, B. T. Dinn, D. Ly, K. N. Sacapano, A. Tajii, C. P. Owens

This study identifies a Lys residue in an extended loop that determines substrate specificity in a Lactobacillus chlorogenic acid esterase by hydrogen bonding to chlorogenic acid.

bioRxiv · May 30, 2023 · PreprintBiochemistry

Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes

S. Brouwer, T. C. Barnett, D. Ly, K. J. Kasper, D. M. De Oliveira, T. Rivera-Hernandez, A. J. Cork, L. McIntyre, M. G. Jespersen, J. Richter, B. L. Schulz, G. Dougan, V. Nizet, K.-Y. Yuen, Y. You, , M. J. Walker

This study identifies prophage-encoded exotoxins in Streptococcus pyogenes that enhance colonization fitness and pathogenesis in scarlet fever.

bioRxiv · May 17, 2020Microbiology

Streptococcus pyogenes M1T1 variants activate caspase-1 and induce an inflammatory neutrophil phenotype

J. G. Williams, D. Ly, N. J. Geraghty, J. D. McArthur, H. Vyas, J. Gorman, J. A. Tsatsaronis, R. Sluyter, M. L. Sanderson-Smith

This study shows that M1T1 GAS variants induce caspase-1 activation and an inflammatory neutrophil phenotype, promoting inflammation but not bacterial clearance.

bioRxiv · Mar 2, 2020 · PreprintMicrobiology

Non-driver somatic alteration burden confers good prognosis in non-small cell lung cancer

D. Wang, N.-A. Pham, T. M. Freeman, V. Raghavan, R. Navab, E. Pasko, J. Chang, C.-Q. Zhu, D. Ly, J. Tong, B. G. Wouters, M. Pintilie, M. F. Moran, F. A. Shepherd, M.-S. Tsao

This study shows that high non-driver somatic alteration burden in NSCLC is linked to better prognosis, including improved survival and immune response.

bioRxiv · Sep 17, 2018 · PreprintCancer Biology