Structural Basis for pre-tRNA Recognition and Processing by the Human tRNA Splicing Endonuclease Complex
C. K. Hayne, K. J. U. Butay, Z. D. Stewart…·R. E. Stanley
This study presents cryo-EM structures of the human TSEN*pre-tRNA complex, revealing its architecture and tRNA binding interfaces, and provides insights into PCH-causing mutations.