Cancer BiologybioRxiv
Small extracellular vesicles promote stiffness-mediated metastasis
A. Sneider, Y. Liu, B. Starich…·D. Wirtz
The paper shows that breast cancer cell-derived small extracellular vesicles (EVs) become more adhesive and metastatic when produced in stiff matrices, promoting cancer spread through enhanced chemotaxis and fibroblast reprogramming.