D. M. Warshaw

This paper studies how kinesin-1 motors transport liposome cargo through 2D and 3D microtubule intersections, finding that spatial relationships bias directional outcomes, with a higher straight-through rate at 3D intersections.

This paper identifies KNX-002 as a specific inhibitor of TgMyoA, reducing parasite motility and disease progression in mice.

This study uses 3D traction force mapping to show that Toxoplasma gondii generates inward-directed forces at a circular zone of attachment to the extracellular matrix, providing directionality to its motility.

This study develops a nanosurf assay to investigate cMyBP-C interactions with actin and myosin, revealing that cMyBP-C inhibits actomyosin motility and that the M-domain and phosphorylation status are critical for this effect.

This paper measures mechanical properties of zebrafish larval swimming muscles, finding they generate high power and have extreme contractile speeds.

This study examines how different MyBP-C isoforms affect contractility in fast- and slow-twitch skeletal muscles using proteomic, biophysical, and modeling approaches.

This study investigates how actin filament density, position, and polarity affect MyoVa-mediated liposome transport in 3D actin networks using in vitro models and computational simulations.