Author

D. Ohadi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1

Frequent Co-Authors

P. Rangamani· 3 shared J. Zhang· 2 shared B. Calabrese· 1 shared B. Ross· 1 shared B. Tenner· 1 shared C. H. Bohrer· 1 shared D. L. Schmitt· 1 shared E. Greenwald· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiophysics

P. Rangamani

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3 papers

Recent·Most cited

Spatially compartmentalized phase regulation of a Ca2+-cAMP-PKA oscillatory circuit

B. Tenner, M. Getz, B. Ross, D. Ohadi, C. H. Bohrer, E. Greenwald, S. Mehta, J. Xiao, P. Rangamani, J. Zhang

The paper shows that spatially distinct cAMP oscillations, in-phase with Ca2+ and out-of-phase with PKA, regulate signaling in pancreatic β cells through nanodomain clustering of adenylyl cyclases and phosphodiesterases.

bioRxiv · Jan 10, 2020Cell Biology

Computational modeling reveals frequency modulation of calcium-cAMP/PKA pathway in dendritic spines

D. Ohadi, D. L. Schmitt, B. Calabrese, S. Halpain, J. Zhang, P. Rangamani

The paper models calcium-induced cAMP/PKA dynamics in dendritic spines, showing that the pathway filters high-frequency calcium inputs to respond only to lower frequencies.

bioRxiv · Aug 5, 2019Biophysics

Geometric control of frequency modulation of cAMP oscillations due to Ca2+-bursts in dendritic spines

D. Ohadi, P. Rangamani

The paper models cAMP dynamics in dendritic spines, showing that geometric factors and enzyme localization control cAMP oscillations.

bioRxiv · Jan 15, 2019Biophysics