Author

D. Potoyan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Organism:Drosophila· 1 Assay:Hi-C· 1

Frequent Co-Authors

J. Roche· 2 shared A. Kumar· 1 shared A. L. Hansen· 1 shared B. S. Tolbert· 1 shared J. D. Levengood· 1 shared M. Di Pierro· 1 shared R. Laghmach· 1 shared S. Kutluay· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersBiochemistry

J. Roche

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Author profile →

3 papers

Recent·Most cited

4D Mesoscale liquid model of nucleus resolves chromatin's radial organization

R. Laghmach, M. Di Pierro, D. Potoyan

The paper develops a physics-based 4D mesoscale liquid model of the nucleus to resolve chromatin's radial organization and its dynamics.

bioRxiv · Sep 21, 2023 · PreprintBiophysics

Thermodynamic Coupling of the tandem RRM domains of hnRNP A1 underlie its Pleiotropic RNA Binding Functions

J. D. Levengood, D. Potoyan, S. Penumutchu, A. Kumar, Y. Wang, A. L. Hansen, S. Kutluay, J. Roche, B. S. Tolbert

This study shows that thermodynamic coupling between tandem RRM domains of hnRNP A1 is essential for its allosteric RNA binding functions and stability under pressure.

bioRxiv · Aug 17, 2023 · PreprintBiochemistry

Conformational landscape of the transcription factor ATF4 is dominated by disordered-mediated inter-domain coupling

U. Patel, S. Siang, D. Potoyan, J. Roche

This study investigates the structural basis of inter-domain interactions in ATF4, revealing that disorder-mediated coupling between transactivation and bZip domains shapes its conformational landscape.

bioRxiv · May 12, 2023 · PreprintBiophysics