D. R. Noguera

This paper develops genetic tools for Novosphingobium aromaticivorans and Rhodobacter sphaeroides to enable efficient gene insertion and expression control using Tn7 transposition and synthetic promoters.

This study reconstructs a genome-scale metabolic model of Nitrospira moscoviensis and validates it using proteomics, 13C-tracer, and metabolomic analysis to elucidate its autotrophic and formate metabolism.

This study identifies a new metabolic pathway in Novosphingobium aromaticivorans for converting phenolic compounds into 2-pyrone-4,6-dicarboxylic acid, improving strain engineering for lignin valorization.

The paper constructs two metabolic models to predict and improve medium-chain fatty acid production in microbial communities using genomic, transcriptomic, and metabolomic data.

This study uses isotope tracing and metabolomics to resolve the central carbon metabolism of an anammox bacterium, revealing discrepancies between genomic predictions and in vivo metabolic fluxes.

This paper isolates and characterizes a Rhodopseudomonas palustris strain capable of anaerobically degrading syringic acid, revealing a novel metabolic pathway distinct from the benzoyl-CoA degradation pathway.

The paper characterizes two MCFA-producing bacteria using multi-omic analysis of an anaerobic microbiome involved in chain elongation from organic waste.

This study uses integrated omics analysis to show that an Accumulibacter strain can simultaneously respire oxygen and nitrate under micro-aerobic conditions, supporting denitrification.

The paper designs and tests new qPCR primers for species-level detection of comammox in low DO activated sludge systems, finding Ca. N. nitrosa is abundant while others are rare.

This study identifies and compares genomic traits of comammox and nitrite-oxidizing Nitrospira strains to understand their ecological and physiological adaptations.