Differential and lasting gene expression changes in circulating CD8 T cells in chronic HCV infection with cirrhosis and related insights on the role of Hedgehog signaling
J. Li, A. Vranjkovic, D. Read, S. P. Delaney, W. L. Stanford, C. L. Cooper, A. M. Crawley
This study examines gene expression changes in CD8 T cells from HCV-infected individuals with varying fibrosis stages, identifying lasting hyperfunction and upregulated Hedgehog signaling in cirrhosis.
bioRxiv · Sep 20, 2023Immunology