Author

I. Winfield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Ecology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

D. Safitri· 2 shared G. Ladds· 2 shared A. Suchankova· 1 shared A. Szitenberg· 1 shared B. Frenguelli· 1 shared B. Haenfling· 1 shared B. Preti· 1 shared C. A. Reynolds· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

D. Safitri

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression

M. Wall, E. Hill, R. Huckstepp, K. Barkan, G. Deganutti, M. Leuenberger, B. Preti, I. Winfield, S. Carvalho, A. Suchankova, H. Wei, D. Safitri, X. Huang, W. Imlach, C. La Mache, , B. Frenguelli

The paper identifies BnOCPA as an A1R agonist that selectively activates Gαob, providing analgesia without cardiorespiratory depression.

bioRxiv · Apr 4, 2020Physiology

Elevated intracellular cAMP concentration mediates growth suppression in glioma cells

D. Safitri, H. Potter, M. Harris, I. Winfield, L. Kopanitsa, H. Y. Yeung, F. Svensson, T. Rahman, M. Harper, D. Bailey, G. Ladds

The paper shows that increasing intracellular cAMP levels via AC activation or PDE inhibition suppresses glioma cell growth, with different mechanisms depending on the PDE inhibitor used.

bioRxiv · Jul 30, 2019Pharmacology & Toxicology

Temporal and spatial variation in distribution of fish environmental DNA in England’s largest lake

L. J. Lawson Handley, D. Read, I. Winfield, H. Kimbell, H. Johnson, J. Li, C. Hahn, R. Blackman, R. Wilcox, R. Donnelly, A. Szitenberg, B. Haenfling

This study examines temporal and spatial variation in fish eDNA distribution in Windermere, finding greater summer spatial structure and species-specific sampling biases.

bioRxiv · Jul 24, 2018Ecology