Author

D. S. Schrump

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

H. Chen· 2 shared L. Gesumaria· 2 shared A. Kumari· 1 shared B. A. Mock· 1 shared C. Klumpp-Thomas· 1 shared C. McKnight· 1 shared C. Thomas· 1 shared D. S. Singer· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

H. Chen

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2 papers

Recent·Most cited

Cancer BiologybioRxivNov 8, 2021

mTOR Inhibition Overcomes RSK3-mediated Resistance to BET Inhibitors in Small Cell Lung Cancer

A. Kumari, L. Gesumaria, Y.-J. Liu…·H. Chen

This study identifies mTOR inhibition as a strategy to overcome RSK3-mediated resistance to BET inhibitors in small cell lung cancer, enhancing apoptosis and antitumor efficacy.

DOI 10.1172/jci.insight.156657

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivOct 25, 2021

BET Inhibitors Target the SCLC-N subtype Small Cell Lung Cancer by Blocking NEUROD1 Transactivation

H. Chen, L. Gesumaria, Y.-K. Park…·D. S. Schrump

This study identifies BET bromodomain proteins as coactivators of NEUROD1 in SCLC, showing that BET inhibitors suppress NEUROD1-target genes and reduce tumor growth.

DOI 10.1158/1541-7786.mcr-22-0594

humanChIP-seq

𝕏 PostBluesky