Author

D. Schulte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

J. Snijder· 3 shared M. Siborova· 2 shared W. Peng· 2 shared A. D. van Zuilen· 1 shared A. Hill· 1 shared A. J. R. Heck· 1 shared A.-L. Luger· 1 shared B. J. C. Janssen· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersBiochemistry

J. Snijder

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry - a perspective.

D. Schulte, M. Siborova, L. Käll, J. Snijder

The paper evaluates using cryoEM and mass spectrometry with a deep-learning tool to sequence antibodies and map epitopes from convalescent serum, showing 80-90% accuracy in variable domain sequencing.

bioRxiv · Jun 21, 2024Biochemistry

Before and after delisting: population dynamics of North Atlantic humpback whales over two decades in the Gulf of Maine

J. Robbins, M. Berube, P. J. Clapham, D. K. Mattila, P. J. Palsboll, R. Asmutis-Silvia, A. Hill, L. J. Howes, S. Landry, S. Lonergan, D. Schulte, J. E. Tackaberry, M. T. Weinrich, R. M. Pace

The paper estimates population dynamics of North Atlantic humpback whales in the Gulf of Maine from 2000 to 2019, finding increased abundance but declining calf survival and sex ratio shifts.

bioRxiv · Feb 4, 2024 · PreprintEcology

Reverse engineering the anti-MUC1 hybridoma antibody 139H2 by mass spectrometry-based de novo sequencing

W. Peng, K. C. A. P. Giesbers, M. Siborova, J. W. Beugelink, M. F. Pronker, D. Schulte, J. Hilkens, B. J. C. Janssen, K. Strijbis, J. Snijder

This paper reverse engineers the anti-MUC1 hybridoma antibody 139H2 using mass spectrometry-based sequencing and validates its properties through various assays.

bioRxiv · Jul 5, 2023 · PreprintBiochemistry

Direct mass spectrometry-based detection and antibody sequencing of Monoclonal Gammopathy of Undetermined Significance from patient serum - a case study.

W. Peng, M. A. den Boer, S. Tamara, N. J. Mokiem, S. P. A. van der Lans, D. Schulte, P.-J. Haas, M. C. Minnema, S. H. M. Rooijakkers, A. D. van Zuilen, A. J. R. Heck, J. Snijder

This paper detects MGUS using LC-MS and determines M-protein sequences from serum, providing molecular detail for monoclonal gammopathies.

bioRxiv · May 22, 2023Immunology

AMP-kinase mediates adaptation of glioblastoma cells to conditions of the tumour microenvironment

N. I. Lorenz, B. Sauer, P. S. Zeiner, M. I. Strecker, A.-L. Luger, D. Schulte, M. Mittelbronn, T. Alekseeva, L. Sevenich, P. N. Harter, C. Münch, J. P. Steinbach, M. W. Ronellenfitsch

This study shows that AMPK is essential for glioblastoma cells to adapt to low energy conditions in the tumor microenvironment, with AMPK inhibition reducing tumor growth and mitochondrial function.

bioRxiv · Mar 25, 2022 · PreprintCancer Biology