RET activation controlled by MAB21L4-CacyBP interaction drives squamous cell carcinoma
A. Srivastava, C. Tommasi, D. Sessions, A. Mah, T. Bencomo, J. M. Garcia, T. Jiang, M. Lee, J. Y. Shen, L. W. Seow, A. Nguyen, K. Rajapakshe, C. Coarfa, K. Y. Tsai, V. Lopez-Pajares, C. S. Lee
This study identifies RET activation driven by MAB21L4-CacyBP interaction as a driver of squamous cell carcinoma and shows RET inhibition as a potential therapeutic strategy.
bioRxiv · Jan 19, 2022 · PreprintCancer Biology