Author

J. M. Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Hyrenius-Wittsten· 1 shared A. Mah· 1 shared A. Nguyen· 1 shared A. S. Lee· 1 shared A. Srivastava· 1 shared B. Liu· 1 shared C. Coarfa· 1 shared C. S. Lee· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperImmunology

A. Hyrenius-Wittsten

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Convergent mutations in phage virion assembly proteins enable evasion of Type I CBASS immunity

D. Richmond-Buccola, S. J. Hobbs, J. M. Garcia, H. Toyoda, J. Gao, S. Shao, A. S. Lee, P. J. Kranzusch

The paper identifies mutations in phage virion assembly proteins that enable evasion of Type I CBASS immunity by altering infection kinetics.

bioRxiv · May 21, 2023Microbiology

RET activation controlled by MAB21L4-CacyBP interaction drives squamous cell carcinoma

A. Srivastava, C. Tommasi, D. Sessions, A. Mah, T. Bencomo, J. M. Garcia, T. Jiang, M. Lee, J. Y. Shen, L. W. Seow, A. Nguyen, K. Rajapakshe, C. Coarfa, K. Y. Tsai, V. Lopez-Pajares, C. S. Lee

This study identifies RET activation driven by MAB21L4-CacyBP interaction as a driver of squamous cell carcinoma and shows RET inhibition as a potential therapeutic strategy.

bioRxiv · Jan 19, 2022 · PreprintCancer Biology

Enhanced Solid Tumor Recognition and T cell Stemness with SynNotch CAR Circuits

A. Hyrenius-Wittsten, Y. Su, M. Park, J. M. Garcia, N. Perry, G. Montgomery, B. Liu, K. T. Roybal

This study identifies ALPPL2 as a tumor-specific antigen and demonstrates that synNotch CAR T cells targeting it improve tumor control by reducing T cell exhaustion.

bioRxiv · Jan 6, 2021 · PreprintImmunology