Author

A. Wollman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:fluorescence / live-cell microscopy· 5 Approach:microscopy & imaging analysis· 5 Research Focus:cell signaling & trafficking· 4 Organism:yeast· 3 Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. C. Leake· 4 shared M. Leake· 3 shared S. Shashkova· 3 shared E. Hedlund· 2 shared S. Hohmann· 2 shared A. Harvgreaves· 1 shared A. Maxwell· 1 shared A. Syeda· 1 shared

Activity by Year

2017-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersBiophysics

M. C. Leake

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Author profile →

7 papers

Recent·Most cited

Single-organelle quantification reveals the stoichiometric and structural variability of carboxysomes dependent on the environment

Y. Sun, A. Wollman, F. Huang, M. C. Leake, L. Liu

The paper determines the absolute protein stoichiometry of carboxysomes and reveals their organizational variability in response to microenvironmental changes.

bioRxiv · May 4, 2019Biophysics

Mapping the 3D genome through high speed single-molecule tracking of functional transcription factors in single living cells

A. Wollman, E. Hedlund, S. Shashkova, M. Leake

The paper introduces a method to map 3D genome organization in living cells using single-molecule tracking of transcription factors in budding yeast.

bioRxiv · Mar 5, 2019Biophysics

Single-molecule imaging of DNA gyrase activity in living Escherichia coli

M. Stracy, A. Wollman, E. Kaja, J. Gapinski, J.-E. Lee, V. Leek, S. McKie, L. Mitchenall, A. Maxwell, D. Sherratt, M. Leake, P. Zawadzki

This study uses single-molecule imaging to analyze DNA gyrase activity in live E. coli, showing gyrase dynamics and supercoil regulation during replication.

bioRxiv · Nov 1, 2018Biophysics

Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome

A. Syeda, A. Wollman, A. Harvgreaves, J. Bruning, P. McGlynn, M. Leake

The paper uses single-molecule live cell imaging to study the dynamic interactions of the bacterial helicase Rep with the replisome and PriC, revealing two distinct mechanisms for overcoming nucleoprotein barriers during DNA replication.

bioRxiv · Sep 29, 2018Biophysics

Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration

K. Haapasalo, A. Wollman, C. de Haas, K. van Kessel, J. van Strijp, M. C. Leake

The paper shows Staphylococcus aureus toxin LukSF dissociates from its receptor to allow renewed ligand binding, facilitating rapid cell lysis and immune evasion.

bioRxiv · Apr 23, 2018Microbiology

The Yeast Mig1 Transcriptional Repressor Is Dephosphorylated By Glucose-Dependent And Independent Mechanisms

S. Shashkova, A. Wollman, M. C. Leake, S. Hohmann

This study identifies both glucose-dependent and independent mechanisms of Mig1 dephosphorylation in yeast, highlighting the role of multiple phosphatases and tyrosine phosphorylation in its regulation.

bioRxiv · Apr 25, 2017Biochemistry

Transcription factor clusters regulate genes in eukaryotic cells

A. Wollman, S. Shashkova, E. Hedlund, R. Friemann, S. Hohmann, M. C. Leake

The paper shows transcription factors form clusters that regulate gene expression in yeast by reducing search times and stabilizing expression.

bioRxiv · Apr 6, 2017Biophysics