Author

D. Subramanyam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. B. Singh· 3 shared R. D. Mote· 2 shared A. Kelkar· 1 shared a. majumdar· 1 shared A. Nandi· 1 shared A. S. Yap· 1 shared A. Sharma· 1 shared B. Gauri Shankar· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersCell Biology

S. B. Singh

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Author profile →

5 papers

Recent·Most cited

Pre-existing tissue mechanical hypertension at adherens junctions disrupts apoptotic extrusion in epithelia

Z. Mann, F. Lim, S. Verma, B. N. Nanavati, J. M. Davies, J. Begun, E. C. Hardeman, P. W. Gunning, D. Subramanyam, A. S. Yap, K. Duszyc

This study shows that pre-existing mechanical tension at adherens junctions impairs apoptotic extrusion in epithelia, and this effect can be reversed by reducing tension.

bioRxiv · Aug 31, 2023Cell Biology

Pathogenic aggregates alter actin organization and cellular viscosity resulting in stalled clathrin mediated endocytosis

S. B. Singh, S. S. Rajput, A. Sharma, V. Ananthanarayanan, A. Nandi, S. P. V. Patil, a. majumdar, D. Subramanyam

This study shows that pathogenic protein aggregates disrupt actin organization and cellular viscosity, impairing clathrin-mediated endocytosis in neurodegenerative conditions.

bioRxiv · Jul 10, 2023 · PreprintCell Biology

Autophagy-cell death balance is maintained by Polycomb-mediated regulation during stem cell differentiation

D. Puri, A. Kelkar, B. Gauri Shankar, D. Subramanyam

The paper shows that Polycomb-mediated regulation of Dram1 maintains autophagy-cell death balance during stem cell differentiation.

bioRxiv · Mar 29, 2022 · PreprintCell Biology

E-cadherin regulates the stability and transcriptional activity of β-catenin in embryonic stem cells

S. Bhattacharyya, R. D. Mote, J. Freimer, S. B. Singh, S. Arumugam, Y. V. Narayana, R. Rajan, D. Subramanyam

This study shows E-cadherin stabilizes and activates β-catenin in mouse ESCs, influencing cell-state-dependent gene expression and differentiation.

bioRxiv · Jul 22, 2021 · PreprintCell Biology

Loss of clathrin heavy chain enhances actin-dependent stiffness of mouse embryonic stem cells

R. D. Mote, J. Yadav, S. B. Singh, M. Tiwari, S. P. Patil, D. Subramanyam

This study shows that loss of clathrin heavy chain in mESCs increases cellular stiffness via actin stress fibers, without restoring pluripotency gene expression.

bioRxiv · May 10, 2020 · PreprintCell Biology