Author

D. Turk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. Usenik· 2 shared J. Lieske· 2 shared P. Y. A. Reinke· 2 shared S. Falke· 2 shared W. Ewert· 2 shared A. Coll· 1 shared A. Herrmann· 1 shared A. Luana C Barra· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

A. Usenik

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural elucidation and antiviral activity of cathepsin L inhibitors with carbonyl and epoxide warheads

S. Falke, J. Lieske, A. Herrmann, J. Loboda, S. Gunther, P. Y. A. Reinke, W. Ewert, K. Karnicar, A. Usenik, N. Lindic, A. Sekirnik, H. Tsuge, V. Turk, H. N. Chapman, W. Hinrichs, , A. Meents

The paper presents crystal structures of cathepsin L inhibitors and evaluates their antiviral activity against SARS-CoV-2.

bioRxiv · Aug 11, 2023 · PreprintBiochemistry

An optimized and validated workflow for developing stable producer cell lines with >99.99% assurance of clonality and high clone recovery

J. Scherzinger, D. Turk, F. Aprile-Garcia

This paper validates an optimized workflow using the UP.SIGHT instrument to achieve high clonality assurance and clone recovery in mammalian cell line development.

bioRxiv · Dec 16, 2022 · PreprintBioengineering

SARS-CoV-2 papain-like protease PLpro in complex with natural compounds reveal allosteric sites for antiviral drug design

V. Srinivasan, H. Brognaro, P. R. Prabhu, E. E. de Souza, S. Guenther, P. Y. A. Reinke, T. J. Lane, H. Ginn, H. Han, W. Ewert, J. Sprenger, F. H. M. Koua, S. Falke, N. Werner, H. Andaleeb, , P

This study identifies three natural compounds that inhibit SARS-CoV-2 PLpro by binding to the ISG15/Ub-S2 allosteric site, showing antiviral activity and potential for drug design.

Communications Biology · Aug 11, 2022Peer-reviewedBiochemistry

A mini-TGA protein, lacking a functional DNA-binding domain, modulates gene expression through heterogeneous association with transcription factors

S. Tomaz, M. Petek, T. Lukan, K. Pogacar, K. Stare, E. Teixeira Prates, D. A. Jacobson, J. Zrimec, G. Bajc, M. Butala, M. Pompe Novak, Q. M. Dudley, N. Patron, A. Taler-Vercic, A. Usenik, , K. Gruden

This study shows that a truncated TGA protein, lacking a DNA-binding domain, modulates gene expression by interacting with other TGA proteins and activating immune-related genes.

bioRxiv · Mar 30, 2022 · PreprintPlant Biology