Author

F. Aprile-Garcia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

R. Sawarkar· 2 shared A. Anandamurugan· 1 shared A. E. Willis· 1 shared A. Herrero-Ruiz· 1 shared A. Reinhardt· 1 shared A. Srivastava· 1 shared B. Hummel· 1 shared C. Lan· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

R. Sawarkar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivApr 10, 2023

HSP70 binds to specific non-coding RNA and regulates human RNA Polymerase III

S. Leone, A. Srivastava, B. Hummel…·R. Sawarkar

This study identifies HSP70's interaction with non-coding RNA transcribed by RNA Polymerase III and shows its role in facilitating transcription of these RNAs.

DOI 10.1016/j.molcel.2024.01.001

humanbulk RNA-seq

𝕏 PostBluesky

BioengineeringbioRxivPreprintDec 16, 2022

An optimized and validated workflow for developing stable producer cell lines with >99.99% assurance of clonality and high clone recovery

J. Scherzinger, D. Turk, F. Aprile-Garcia

This paper validates an optimized workflow using the UP.SIGHT instrument to achieve high clonality assurance and clone recovery in mammalian cell line development.

DOI 10.1101/2022.12.16.520697

mouseexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivAug 1, 2022

Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation

C. Lan, J. Kim, S. Ulferts…·T. Hugel

The paper uses fluorescence microscopy to study protein clusters before condensation, finding dynamic clusters that are not freely diffusing and exist even in unstressed cells.

DOI 10.1038/s41467-023-40540-2

humanfluorescence / live-cell microscopy

𝕏 PostBluesky