Role of the CTCF Binding Site in Human T-Cell Leukemia Virus-1 Pathogenesis
A. Joseph, X. Cheng, J. Harding, J. Al-Saleem, P. Green, D. Veis, D. A. Rauch, L. Ratner
This study shows that the CTCF binding site in HTLV-1 regulates viral pathogenesis by affecting proviral load, Tax expression, and T-cell activation in humanized mice.
bioRxiv · May 28, 2024Microbiology