Author

A. Joseph

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Cancer Biology· 2 Bioengineering· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Organism:human· 5 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

L. Ratner· 3 shared D. A. Rauch· 2 shared J. Harding· 2 shared A. Badrinarayanan· 1 shared A. Gupta· 1 shared A. Mukherjee· 1 shared A. Naqvi· 1 shared A. Panfil· 1 shared

Activity by Year

2016-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

L. Ratner

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

HTLV-1 infected T cells cause bone loss via small extracellular vesicles

N. K. Pokhrel, A. Panfil, H. Habib, S. Seeniraj, A. Joseph, D. Rauch, R. Sprung, P. E. Gilmore, Q. Zhang, R. R. Townsend, L. Yu, A. S. Yilmaz, R. Aurora, W. Park, L. Ratner, , D. J. Veis

This study shows HTLV-1 infected T cells release small extracellular vesicles that promote bone loss by stimulating osteoclasts, independent of RANKL expression.

Journal of Extracellular Vesicles · Oct 10, 2024Peer-reviewedCancer Biology

Role of the CTCF Binding Site in Human T-Cell Leukemia Virus-1 Pathogenesis

A. Joseph, X. Cheng, J. Harding, J. Al-Saleem, P. Green, D. Veis, D. A. Rauch, L. Ratner

This study shows that the CTCF binding site in HTLV-1 regulates viral pathogenesis by affecting proviral load, Tax expression, and T-cell activation in humanized mice.

bioRxiv · May 28, 2024Microbiology

Single-Cell Transcriptomic Analysis of Kaposi Sarcoma

D. A. Rauch, P. Valino Ramos, M. Khanfar, J. Harding, A. Joseph, O. Griffith, M. Griffith, L. Ratner

This study uses single-cell RNA sequencing to analyze Kaposi Sarcoma tumors and blood samples, identifying KSHV-infected cell types and their biomarkers, and showing changes with therapy.

bioRxiv · May 1, 2024Cancer Biology

Deep learning classification of ex vivo human colon tissues using spectroscopic OCT

W. Kendall, Q. Tian, S. Zhao, S. Mirminachi, A. Joseph, D. Dufault, C. Shi, J. Roper, A. Wax

This study uses deep learning to classify ex vivo human colon tissues with spectroscopic OCT, achieving 88.9% accuracy in distinguishing tissue types.

bioRxiv · Sep 4, 2023 · PreprintPathology

Requirement for specific bacterial genome maintenance pathways in repair of C8-linked pyrrolobenzodiazepine (PBD) bi-aryl monomer-mediated DNA damage

A. Joseph, K. Nahar, S. Daw, M. Hasan, R. Lo, T. B. K. Le, K. Rahman, A. Badrinarayanan

This study investigates how C8-linked PBD bi-aryl monomers cause DNA damage in Caulobacter crescentus and identifies the repair mechanisms required for survival.

bioRxiv · Jun 10, 2022 · PreprintMicrobiology

Detection of NDM-1, VIM-1 and AIM-type Metallo-beta-lactamase genes in Gram-negative bacteria isolated from clinical samples in Tamil Nadu

P. Manohar, A. Joseph, K. B, P. AnuPriya, S. S. Mani, V. Varsha, N. Ramesh

The paper investigates carbapenem-resistant Gram-negative bacteria in clinical samples from Tamil Nadu, identifying specific metallo-beta-lactamase genes in resistant isolates.

bioRxiv · Nov 29, 2020 · PreprintMicrobiology

PRAK-03202: A triple antigen VLP vaccine candidate against SARS CoV-2

S. Mazumder, R. Rastogi, A. Undale, K. Arora, N. M. Arora, B. P. Das Purkayastha, D. Kumar, A. Joseph, B. Mali, V. B. Arya, S. Kalyanaraman, A. Mukherjee, A. Gupta, S. Potdar, S. S. Roy, , P. K. Kundu

This paper develops a triple antigen VLP vaccine candidate, PRAK-03202, against SARS-CoV-2 and shows it induces neutralizing antibodies and Th1 immune responses in mice.

bioRxiv · Oct 30, 2020Immunology

Chemotactic synthetic vesicles: design and applications in blood brain barrier crossing

A. Joseph, C. Contini, D. Cecchin, S. Nyberg, L. Ruiz-Perez, J. Gaitzsch, G. Fullstone, X. Tian, J. Azizi, J. Preston, G. Volpe, G. Battaglia

This paper designs synthetic vesicles that exhibit chemotaxis by converting glucose, showing improved brain penetration compared to non-chemotactic systems.

bioRxiv · Jun 29, 2016Bioengineering