Author

L. Ratner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Joseph· 3 shared D. A. Rauch· 2 shared J. Harding· 2 shared A. Panfil· 1 shared A. S. Yilmaz· 1 shared B. Diaz· 1 shared B. Grubbs· 1 shared D. Accili· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCancer Biology

A. Joseph

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

HTLV-1 infected T cells cause bone loss via small extracellular vesicles

N. K. Pokhrel, A. Panfil, H. Habib, S. Seeniraj, A. Joseph, D. Rauch, R. Sprung, P. E. Gilmore, Q. Zhang, R. R. Townsend, L. Yu, A. S. Yilmaz, R. Aurora, W. Park, L. Ratner, , D. J. Veis

This study shows HTLV-1 infected T cells release small extracellular vesicles that promote bone loss by stimulating osteoclasts, independent of RANKL expression.

Journal of Extracellular Vesicles · Oct 10, 2024Peer-reviewedCancer Biology

Role of the CTCF Binding Site in Human T-Cell Leukemia Virus-1 Pathogenesis

A. Joseph, X. Cheng, J. Harding, J. Al-Saleem, P. Green, D. Veis, D. A. Rauch, L. Ratner

This study shows that the CTCF binding site in HTLV-1 regulates viral pathogenesis by affecting proviral load, Tax expression, and T-cell activation in humanized mice.

bioRxiv · May 28, 2024Microbiology

Single-Cell Transcriptomic Analysis of Kaposi Sarcoma

D. A. Rauch, P. Valino Ramos, M. Khanfar, J. Harding, A. Joseph, O. Griffith, M. Griffith, L. Ratner

This study uses single-cell RNA sequencing to analyze Kaposi Sarcoma tumors and blood samples, identifying KSHV-infected cell types and their biomarkers, and showing changes with therapy.

bioRxiv · May 1, 2024Cancer Biology

Triple Notch/Tgfβ/FoxO1 blockade converts multiple intestinal sub-lineages into β-like cells and lowers glycemia in diabetic animals

W. Du, J. Wang, T. Kuo, L. Wang, W. McKimpson, J. Son, H. Watanabe, T. Kitamoto, L. Yunkyoung, L. Ratner, K. McCune, Y.-W. Chen, B. Grubbs, M. Thornton, J. Fan, , D. Accili

bioRxiv · Mar 21, 2022 · PreprintCell Biology