Cancer BiologyACS NanoPeer-reviewed
Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity
Xin Luo, Fernanda Grande Kugeratski, Dara P. Dowlatshahi…·Raghu Kalluri
This study engineers extracellular vesicles from epithelial cells to express immunomodulatory proteins, showing they can induce both positive and negative T cell co-stimulation in cancer and autoimmunity.