BiochemistryNucleic Acids ResearchPeer-reviewed
DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces
Simona M. Miron, Pierre Legrand, Pauline Dupaigne…·Alex N. Zelensky
This paper explains how BRCA2's FxxA and FxPP motifs bind to DMC1 and RAD51 via distinct interfaces, stabilizing recombinase filaments and explaining functional differences between these proteins.