Author

Denice M. Arnold

Howard Hughes Medical Institute

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Neuroscience· 1

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Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

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Amita SehgaliD· 1 shared Gregory ArtiushiniD· 1 shared Shirley ZhangiD· 1 shared Zhifeng Yue· 1 shared

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2018-2018 · peak 1/yr

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Amita SehgalORCID

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1 paper

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NeuroscienceCellPeer-reviewedMar 1, 2018

A circadian clock in the blood-brain barrier regulates xenobiotic efflux from the brain

Shirley Zhang, Zhifeng Yue, Denice M. Arnold…·Amita Sehgal

The paper shows that the Drosophila blood-brain barrier has a circadian permeability rhythm driven by a clock in perineurial glia, with nighttime increased permeability enhancing drug efficacy.

253 citationstop 1%

Drosophilastatistical model

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