Author

E. Abramson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Shimizu· 1 shared C. Hardman· 1 shared E. Semenza· 1 shared L. D. Hester· 1 shared L. Reilly· 1 shared M. D. Kornberg· 1 shared M. Donowitz· 1 shared P. A. Wender· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Shimizu

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loss of PI3-kinase activity of inositol polyphosphate multikinase impairs PDK1-mediated AKT activation, cell migration, and intestinal homeostasis

P. Guha, L. Reilly, E. Semenza, E. Abramson, S. Mishra, Y. Sei, S. A. Wank, M. Donowitz, S. Snyder

This study shows that IPMK's PI3-kinase activity is essential for PDK1 membrane localization, which activates AKT and supports intestinal homeostasis and regeneration.

iScience · May 1, 2023Peer-reviewedCell Biology

Designed PKC-targeting bryostatin analogs modulate innate immunity and neuroinflammation

E. Abramson, C. Hardman, A. Shimizu, S. Hwang, L. D. Hester, S. H. Snyder, P. A. Wender, P. M. Kim, M. D. Kornberg

The paper shows that bryologs, synthetic analogs of bryostatin-1, reduce neuroinflammation by targeting PKC in innate immune cells, suggesting their potential as therapeutic agents for neuroinflammatory diseases.

bioRxiv · Sep 12, 2020Immunology