Unacylated ghrelin and AZP531 suppress the 3D growth of breast cancers
C. C. Au, J. B. Furness, K. Britt, S. Oshchepkova, H. Ladumor, K. Y. Soo, B. Callaghan, C. Gerard, G. Inghirami, V. Mittal, Y. Wang, X.-Y. Huang, J. A. Spector, E. Andreopoulou, P. Zumbo, , K. A. Brown
This study shows unacylated ghrelin and its analog AZP531 inhibit breast cancer growth in 3D cultures and xenografts by suppressing MAPK signaling and inducing apoptosis.
bioRxiv · Jan 22, 2020 · PreprintCancer Biology