Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
L. A. Nease, K. P. Church, I. Delclaux, S. Murakami, M. A. Amiama, M. Zerhouni, G. Cascio, R. O. Hughes, P. Zumbo, L. E. Dow, S. R. Jaffrey, D. Betel, E. Piskounova
This study shows that FTSJ1-mediated tRNASec methylation enhances oxidative stress resistance and metastatic colonization in melanoma.
bioRxiv · Oct 2, 2023Cancer Biology
C. Zhang, N. Saurat, D. Cornacchia, S. Y. Chung, T. Sikder, A. Minotti, L. Studer, D. Betel
The paper introduces RNAge, a transcriptional age score, to quantify cellular aging and identify age-modulating compounds in hPSC-derived cells.
bioRxiv · Jul 3, 2023 · PreprintCell Biology
A. Schietinger, G. Espinosa-Carrasco, A. Dave, A. Scrivo, H.-S. Lee, B. M. Burt, P. Zumbo, D. Betel, M. Hellmann
This study identifies intratumoral CD4 T cell::CD8 T cell::APC triads as essential for effective adoptive T cell therapy and anti-tumor immunity in both preclinical models and human lung cancer patients.
bioRxiv · Jul 3, 2023 · PreprintImmunology
E. Cortada, J. Yao, Y. Xia, F. Dundar, P. Zumbo, B. Yang, A. Rubio-Navarro, B. Perder, M. Qiu, A. M. Pettinato, E. A. Homan, L. Stoll, D. Betel, J. Cao, J. Lo
This study compares systemic and cardiac inflammatory responses to injury in mice and zebrafish using single-cell transcriptomics, revealing distinct monocyte/macrophage transcriptional clusters and divergent responses between species.
bioRxiv · Mar 15, 2023 · PreprintCell Biology
D. J. Falvo, A. Grimont, P. Zumbo, J. L. Yang, A. Osterhoudt, G. Pan, A. F. Rendeiro, J. E. Wilkinson, F. Dündar, O. Elemento, R. K. Yantiss, D. Betel, R. Koche, R. Chandwani
This study shows that inflammation leaves an epigenetic memory in pancreatic acinar cells, affecting their lineage plasticity and tumorigenesis in response to subsequent stress.
bioRxiv · Nov 1, 2021Cancer Biology
S. S. Chandran, J. Ma, M. G. Klatt, F. Dundar, C. Bandlamudi, P. C. Razavi, H. Y. Wen, B. Weigelt, P. Zumbo, S. N. Fu, L. B. Banks, W. D. Bestman, A. Drilon, D. Betel, D. A. Scheinberg, , C. A. Klebanoff
The paper investigates the immunogenicity of a public neoantigen derived from mutated PIK3CA, showing it is recognized by T cells and presents a framework for immunotherapy.
bioRxiv · Apr 8, 2021 · PreprintImmunology
Y. Ren, s. h. huang, A. Macedo, A. Ward, W. Conce, T. Klevorn, L. Leyre, D. Chan, R. Truong, T. Rohwetter, P. Zumbo, F. Dundar, D. Betel, C. Kovacs, E. Benko, , B. Jones
This study shows BCL-XL antagonists reduce HIV in a cell model of latency but not in ex vivo reservoirs, suggesting resistance in true reservoir cells.
bioRxiv · Nov 25, 2020 · PreprintMicrobiology
C. C. Au, J. B. Furness, K. Britt, S. Oshchepkova, H. Ladumor, K. Y. Soo, B. Callaghan, C. Gerard, G. Inghirami, V. Mittal, Y. Wang, X.-Y. Huang, J. A. Spector, E. Andreopoulou, P. Zumbo, , K. A. Brown
This study shows unacylated ghrelin and its analog AZP531 inhibit breast cancer growth in 3D cultures and xenografts by suppressing MAPK signaling and inducing apoptosis.
bioRxiv · Jan 22, 2020 · PreprintCancer Biology