Pharmacology & ToxicologybioRxiv
In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3
G. Callejo, L. A. Pattison, J. C. Greenhalgh…·T. Rahman
The paper identifies guanabenz and sephin1 as new allosteric modulators of ASIC3 through in silico screening of FDA-approved drugs and electrophysiological validation.
DOI 10.1016/j.bcp.2020.113834