DENND2B activates Rab35 at the intercellular bridge regulating cytokinetic abscission and tetraploidy
R. Kumar, V. Francis, M. S. Ioannou, A. Aguila, E. Banks, G. Kulasekaran, M. Khan, P. S. McPherson
This study identifies DENND2B as a Rab35 GEF that regulates cytokinetic abscission and prevents tetraploidy by modulating actin dynamics and the NoCut checkpoint.
bioRxiv · Jan 12, 2023Cell Biology