DENND2B activates Rab35 at the intercellular bridge regulating cytokinetic abscission and tetraploidy
R. Kumar, V. Francis, M. S. Ioannou…·P. S. McPherson
This study identifies DENND2B as a Rab35 GEF that regulates cytokinetic abscission and prevents tetraploidy by modulating actin dynamics and the NoCut checkpoint.