The HP1γ epigenetic silencer dampens IFN-γ response at the gut epithelial barrier
Y. Chang, J. Mata-Garrido, C. desterke, E. Batsche, A. Hamai, S. Youssouf, D. Skurnik, A. Jalil, J.-C. Beche, E. Piaggio, L. Arbibe, Y. C. Marchand
This study identifies HP1γ as an epigenetic repressor of IFN-γ responsive genes at the gut epithelial barrier, showing its role in dampening immune responses.
bioRxiv · Dec 27, 2022 · PreprintImmunology